Keratin 14 Colorimetric Cell-Based ELISA
The Keratin 14 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor Keratin 14 protein expression profile in cells. The kit can be used for measuring the relative amounts of Keratin 14 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on Keratin 14.
Product Specifications
Synonyms
Keratin, type I cytoskeletal 14; Cytokeratin-14; CK-14; Keratin-14; K14; KRT14
Gene Name
KRT14
UniProt
P02533
Reactivity
Human, Mouse, Rat
Tissue Specificity
Detected in the basal layer, lowered within the more apically located layers specifically in the stratum spinosum, stratum granulosum but is not detected in stratum corneum. Strongly expressed in the outer root sheath of anagen follicles but not in the germinative matrix, inner root sheath or hair. Found in keratinocytes surrounding the club hair during telogen.
Applications
ELISA
Detection Range
> 5000 cells/well
Function
The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro.
Molecular Weight
51561 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Keratin, type I cytoskeletal 14
Subcellular Location
Cytoplasm. Nucleus. Expressed in both as a filamentous pattern.
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