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XRCC1 Colorimetric Cell-Based ELISA Kit

The XRCC1 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor XRCC1 protein expression profile in cells. The kit can be used for measuring the relative amounts of XRCC1 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on XRCC1.

Product Specifications

Synonyms

DNA repair protein XRCC1; X-ray repair cross-complementing protein 1; XRCC1

Gene Name

XRCC1

UniProt

P18887

Reactivity

Human, Mouse, Rat

Tissue Specificity

Expressed in fibroblasts, retinal pigmented epithelial cells and lymphoblastoid cells (at protein level) .

Applications

ELISA

Detection Range

> 5000 cells/well

Function

Involved in DNA single-strand break repair by mediating the assembly of DNA break repair protein complexes. Probably during DNA repair, negatively regulates ADP-ribose levels by modulating ADP-ribosyltransferase PARP1 activity.

Molecular Weight

69477 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Other Gene Names

DNA repair protein XRCC1

Subcellular Location

Nucleus. Moves from the nucleoli to the global nuclear chromatin upon DNA damage.

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