XPA Colorimetric Cell-Based ELISA Kit
The XPA Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor XPA protein expression profile in cells. The kit can be used for measuring the relative amounts of XPA in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on XPA.
Product Specifications
Synonyms
DNA repair protein complementing XP-A cells; Xeroderma pigmentosum group A-complementing protein; XPA; XPAC
Gene Name
XPA
UniProt
P23025
Reactivity
Human, Mouse
Tissue Specificity
Expressed in various cell lines and in skin fibroblasts.
Applications
ELISA
Detection Range
> 5000 cells/well
Function
Involved in DNA excision repair. Initiates repair by binding to damaged sites with various affinities, depending on the photoproduct and the transcriptional state of the region. Required for UV-induced CHEK1 phosphorylation and the recruitment of CEP164 to cyclobutane pyrimidine dimmers (CPD), sites of DNA damage after UV irradiation.
Molecular Weight
31368 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
DNA repair protein complementing XP-A cells
Subcellular Location
Nucleus.
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