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Uba2 Colorimetric Cell-Based ELISA Kit

The Uba2 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor Uba2 protein expression profile in cells. The kit can be used for measuring the relative amounts of Uba2 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on Uba2.

Product Specifications

Synonyms

SUMO-activating enzyme subunit 2;6.3.2.-; Anthracycline-associated resistance ARX; Ubiquitin-like 1-activating enzyme E1B; Ubiquitin-like modifier-activating enzyme 2; UBA2; SAE2, UBLE1B; HRIHFB2115

Gene Name

UBA2

UniProt

Q9UBT2

Reactivity

Human

Applications

ELISA

Detection Range

> 5000 cells/well

Function

The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.

Molecular Weight

71224 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=EKC1584

Product MSDS

https://www.bosterbio.com/msds?sku=EKC1584

Other Gene Names

SUMO-activating enzyme subunit 2

Subcellular Location

Cytoplasm. Nucleus. Shuttles between the cytoplasm and the nucleus, sumoylation is required either for nuclear translocation or nuclear retention.

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