Uba2 Colorimetric Cell-Based ELISA Kit
The Uba2 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor Uba2 protein expression profile in cells. The kit can be used for measuring the relative amounts of Uba2 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on Uba2.
Product Specifications
Synonyms
SUMO-activating enzyme subunit 2;6.3.2.-; Anthracycline-associated resistance ARX; Ubiquitin-like 1-activating enzyme E1B; Ubiquitin-like modifier-activating enzyme 2; UBA2; SAE2, UBLE1B; HRIHFB2115
Gene Name
UBA2
UniProt
Q9UBT2
Reactivity
Human
Applications
ELISA
Detection Range
> 5000 cells/well
Function
The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.
Molecular Weight
71224 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
SUMO-activating enzyme subunit 2
Subcellular Location
Cytoplasm. Nucleus. Shuttles between the cytoplasm and the nucleus, sumoylation is required either for nuclear translocation or nuclear retention.
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