Tyrosinase Colorimetric Cell-Based ELISA Kit
The Tyrosinase Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor Tyrosinase protein expression profile in cells. The kit can be used for measuring the relative amounts of Tyrosinase in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on Tyrosinase.
Product Specifications
Synonyms
Tyrosinase;1.14.18.1; LB24-AB; Monophenol monooxygenase; SK29-AB; Tumor rejection antigen AB; TYR
Gene Name
TYR
UniProt
P14679
Reactivity
Human
Applications
ELISA
Detection Range
> 5000 cells/well
Function
This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine. In addition to hydroxylating tyrosine to DOPA (3,4- dihydroxyphenylalanine), also catalyzes the oxidation of DOPA to DOPA-quinone, and possibly the oxidation of DHI (5,6- dihydroxyindole) to indole-5,6 quinone.
Molecular Weight
60393 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Tyrosinase
Subcellular Location
Melanosome membrane; Single-pass type I membrane protein. Melanosome. Proper trafficking to melanosome is regulated by SGSM2, ANKRD27, RAB9A, RAB32 and RAB38.
Frequently Asked Questions
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