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TRXR2 Colorimetric Cell-Based ELISA Kit

The TRXR2 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor TRXR2 protein expression profile in cells. The kit can be used for measuring the relative amounts of TRXR2 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on TRXR2.

Product Specifications

Synonyms

Thioredoxin reductase 2, mitochondrial;1.8.1.9; Selenoprotein Z; SelZ; TR-beta; Thioredoxin reductase TR3; TXNRD2; KIAA1652, TRXR2

Gene Name

TXNRD2

UniProt

Q9NNW7

Reactivity

Human, Mouse, Rat

Tissue Specificity

Highly expressed in the prostate, ovary, liver, testis, uterus, colon and small intestine. Intermediate levels in brain, skeletal muscle, heart and spleen. Low levels in placenta, pancreas, thymus and peripheral blood leukocytes. According to PubMed:10608886, high levels in kidney, whereas according to PubMed:9923614, levels are low.

Applications

ELISA

Detection Range

> 5000 cells/well

Function

Maintains thioredoxin in a reduced state. Implicated in the defenses against oxidative stress. May play a role in redox- regulated cell signaling.

Molecular Weight

56507 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Other Gene Names

Thioredoxin reductase 2, mitochondrial

Subcellular Location

Mitochondrion.

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