TOP2A Colorimetric Cell-Based ELISA Kit
The TOP2A Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor TOP2A protein expression profile in cells. The kit can be used for measuring the relative amounts of TOP2A in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on TOP2A.
Product Specifications
Synonyms
DNA topoisomerase 2-alpha;5.99.1.3; DNA topoisomerase II, alpha isozyme; TOP2A; TOP2
Gene Name
TOP2A
UniProt
P11388
Reactivity
Human
Applications
ELISA
Detection Range
> 5000 cells/well
Function
Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation (By similarity) .
Molecular Weight
174385 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
DNA topoisomerase 2-alpha
Subcellular Location
Cytoplasm. Nucleus, nucleoplasm. Generally located in the nucleoplasm.
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