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TOP2A Colorimetric Cell-Based ELISA Kit

The TOP2A Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor TOP2A protein expression profile in cells. The kit can be used for measuring the relative amounts of TOP2A in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on TOP2A.

Product Specifications

Synonyms

DNA topoisomerase 2-alpha;5.99.1.3; DNA topoisomerase II, alpha isozyme; TOP2A; TOP2

Gene Name

TOP2A

UniProt

P11388

Reactivity

Human

Applications

ELISA

Detection Range

> 5000 cells/well

Function

Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation (By similarity) .

Molecular Weight

174385 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=EKC1571

Product MSDS

https://www.bosterbio.com/msds?sku=EKC1571

Other Gene Names

DNA topoisomerase 2-alpha

Subcellular Location

Cytoplasm. Nucleus, nucleoplasm. Generally located in the nucleoplasm.

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