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TOB1 Colorimetric Cell-Based ELISA Kit

The TOB1 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor TOB1 protein expression profile in cells. The kit can be used for measuring the relative amounts of TOB1 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on TOB1.

Product Specifications

Synonyms

Protein Tob1; Transducer of erbB-2 1; TOB1; TOB, TROB1

Gene Name

TOB1

UniProt

P50616

Reactivity

Human, Mouse, Rat

Tissue Specificity

Ubiquitous.

Applications

ELISA

Detection Range

> 5000 cells/well

Function

Anti-proliferative protein; the function is mediated by association with deadenylase subunits of the CCR4-NOT complex (PubMed:8632892, PubMed:23236473) . Mediates CPEB3-accelerated mRNA deadenylation by binding to CPEB3 and recruiting CNOT7 which leads to target mRNA deadenylation and decay (PubMed:21336257) .

Molecular Weight

38155 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Other Gene Names

Protein Tob1

Subcellular Location

Cytoplasm. Nucleus. Only a small fraction localizes to the cytoplasm except in late S-phase where more than half of proteins become cytoplasmic.

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