TOB1 Colorimetric Cell-Based ELISA Kit
The TOB1 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor TOB1 protein expression profile in cells. The kit can be used for measuring the relative amounts of TOB1 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on TOB1.
Product Specifications
Synonyms
Protein Tob1; Transducer of erbB-2 1; TOB1; TOB, TROB1
Gene Name
TOB1
UniProt
P50616
Reactivity
Human, Mouse, Rat
Tissue Specificity
Ubiquitous.
Applications
ELISA
Detection Range
> 5000 cells/well
Function
Anti-proliferative protein; the function is mediated by association with deadenylase subunits of the CCR4-NOT complex (PubMed:8632892, PubMed:23236473) . Mediates CPEB3-accelerated mRNA deadenylation by binding to CPEB3 and recruiting CNOT7 which leads to target mRNA deadenylation and decay (PubMed:21336257) .
Molecular Weight
38155 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Protein Tob1
Subcellular Location
Cytoplasm. Nucleus. Only a small fraction localizes to the cytoplasm except in late S-phase where more than half of proteins become cytoplasmic.
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