Synuclein Colorimetric Cell-Based ELISA Kit

The Synuclein Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor Synuclein protein expression profile in cells. The kit can be used for measuring the relative amounts of Synuclein in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on Synuclein.

Product Specifications

Synonyms

Alpha-synuclein; Non-A beta component of AD amyloid; Non-A4 component of amyloid precursor; NACP; SNCA; NACP, PARK1

Gene Name

SNCA

UniProt

P37840

Reactivity

Human, Mouse, Rat

Tissue Specificity

Expressed principally in brain but is also expressed in low concentrations in all tissues examined except in liver. Concentrated in presynaptic nerve terminals.

Applications

ELISA

Detection Range

> 5000 cells/well

Function

May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.