SSB Colorimetric Cell-Based ELISA Kit
The SSB Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor SSB protein expression profile in cells. The kit can be used for measuring the relative amounts of SSB in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on SSB.
Product Specifications
Synonyms
Lupus La protein; La autoantigen; La ribonucleoprotein; Sjoegren syndrome type B antigen; SS-B; SSB
Gene Name
SSB
UniProt
P05455
Reactivity
Human
Applications
ELISA
Detection Range
> 5000 cells/well
Function
Binds to the 3' poly (U) terminus of nascent RNA polymerase III transcripts, protecting them from exonuclease digestion and facilitating their folding and maturation (PubMed:3192525, PubMed:2470590) . In case of Coxsackievirus B3 infection, binds to the viral internal ribosome entry site (IRES) and stimulates the IRES-mediated translation (PubMed:12384597) .
Molecular Weight
46837 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Lupus La protein
Subcellular Location
Nucleus.
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