SEPARASE Colorimetric Cell-Based ELISA Kit
The SEPARASE Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor SEPARASE protein expression profile in cells. The kit can be used for measuring the relative amounts of SEPARASE in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on SEPARASE.
Product Specifications
Synonyms
Separin;3.4.22.49; Caspase-like protein ESPL1; Extra spindle poles-like 1 protein; Separase; ESPL1; ESP1, KIAA0165
Gene Name
ESPL1
UniProt
Q14674
Reactivity
Human, Mouse
Applications
ELISA
Detection Range
> 5000 cells/well
Function
Caspase-like protease, which plays a central role in the chromosome segregation by cleaving the SCC1/RAD21 subunit of the cohesin complex at the onset of anaphase. During most of the cell cycle, it is inactivated by different mechanisms.
Molecular Weight
233175 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Separin
Subcellular Location
Cytoplasm. Nucleus.
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