RIT1 Colorimetric Cell-Based ELISA Kit
The RIT1 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor RIT1 protein expression profile in cells. The kit can be used for measuring the relative amounts of RIT1 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on RIT1.
Product Specifications
Synonyms
GTP-binding protein Rit1; Ras-like protein expressed in many tissues; Ras-like without CAAX protein 1; RIT1; RIBB, RIT, ROC1
Gene Name
RIT1
UniProt
Q92963
Reactivity
Human, Mouse
Tissue Specificity
Expressed in many tissues.
Applications
ELISA
Detection Range
> 5000 cells/well
Function
Plays a crucial role in coupling NGF stimulation to the activation of both EPHB2 and MAPK14 signaling pathways and in NGF- dependent neuronal differentiation. Involved in ELK1 transactivation through the Ras-MAPK signaling cascade that mediates a wide variety of cellular functions, including cell proliferation, survival, and differentiation.
Molecular Weight
25145 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
GTP-binding protein Rit1
Subcellular Location
Cell membrane.
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