Rhodopsin Colorimetric Cell-Based ELISA Kit

The Rhodopsin Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor Rhodopsin protein expression profile in cells. The kit can be used for measuring the relative amounts of Rhodopsin in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on Rhodopsin.

Product Specifications

Synonyms

Rhodopsin; Opsin-2; RHO; OPN2

Gene Name

RHO

UniProt

P08100

Reactivity

Human, Mouse, Rat

Tissue Specificity

Rod shaped photoreceptor cells which mediate vision in dim light.

Applications

ELISA

Detection Range

> 5000 cells/well

Function

Photoreceptor required for image-forming vision at low light intensity (PubMed:8107847, PubMed:7846071) . Required for photoreceptor cell viability after birth (PubMed:2215617, PubMed:12566452) . Light-induced isomerization of the chromophore 11-cis-retinal to all-trans-retinal triggers a conformational change that activates signaling via G-proteins (PubMed:8107847, PubMed:28524165, PubMed:26200343, PubMed:28753425) . Subsequent receptor phosphorylation mediates displacement of the bound G- protein alpha subunit by the arrestin SAG and terminates signaling (PubMed:28524165, PubMed:26200343) .

Molecular Weight

38893 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=EKC1505

Product MSDS

https://www.bosterbio.com/msds?sku=EKC1505

Other Gene Names

Rhodopsin

Subcellular Location

Membrane; Multi- pass membrane protein. Cell projection, cilium, photoreceptor outer segment. Synthesized in the inner segment (IS) of rod photoreceptor cells before vectorial transport to disk membranes in the rod outer segment (OS) photosensory cilia.