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PIP5K Colorimetric Cell-Based ELISA Kit

The PIP5K Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor PIP5K protein expression profile in cells. The kit can be used for measuring the relative amounts of PIP5K in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on PIP5K.

Product Specifications

Synonyms

1-phosphatidylinositol 3-phosphate 5-kinase; Phosphatidylinositol 3-phosphate 5-kinase;2.7.1.150; FYVE finger-containing phosphoinositide kinase; PIKfyve; Phosphatidylinositol 3-phosphate 5-kinase type III; PIPkin-III; Type III PIP kinase; PIKFYVE; KIAA0981, PIP5K3

Gene Name

PIKFYVE

UniProt

Q9Y2I7

Reactivity

Human, Mouse

Applications

ELISA

Detection Range

> 5000 cells/well

Function

The PI (3,5) P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns (3,5) P2) . Catalyzes the phosphorylation of phosphatidylinositol 3-phosphate on the fifth hydroxyl of the myo- inositol ring, to form phosphatidylinositol 3,5-bisphosphate. Required for endocytic-vacuolar pathway and nuclear migration. Plays a role in the biogenesis of endosome carrier vesicles (ECV) / multivesicular bodies (MVB) transport intermediates from early endosomes.

Molecular Weight

237136 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=EKC1461

Product MSDS

https://www.bosterbio.com/msds?sku=EKC1461

Other Gene Names

1-phosphatidylinositol 3-phosphate 5-kinase

Subcellular Location

Endosome membrane. Mainly associated with membranes of the late endocytic pathway.

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