PIP5K Colorimetric Cell-Based ELISA Kit
The PIP5K Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor PIP5K protein expression profile in cells. The kit can be used for measuring the relative amounts of PIP5K in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on PIP5K.
Product Specifications
Synonyms
1-phosphatidylinositol 3-phosphate 5-kinase; Phosphatidylinositol 3-phosphate 5-kinase;2.7.1.150; FYVE finger-containing phosphoinositide kinase; PIKfyve; Phosphatidylinositol 3-phosphate 5-kinase type III; PIPkin-III; Type III PIP kinase; PIKFYVE; KIAA0981, PIP5K3
Gene Name
PIKFYVE
UniProt
Q9Y2I7
Reactivity
Human, Mouse
Applications
ELISA
Detection Range
> 5000 cells/well
Function
The PI (3,5) P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns (3,5) P2) . Catalyzes the phosphorylation of phosphatidylinositol 3-phosphate on the fifth hydroxyl of the myo- inositol ring, to form phosphatidylinositol 3,5-bisphosphate. Required for endocytic-vacuolar pathway and nuclear migration. Plays a role in the biogenesis of endosome carrier vesicles (ECV) / multivesicular bodies (MVB) transport intermediates from early endosomes.
Molecular Weight
237136 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
1-phosphatidylinositol 3-phosphate 5-kinase
Subcellular Location
Endosome membrane. Mainly associated with membranes of the late endocytic pathway.
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