Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

PDCD4 Colorimetric Cell-Based ELISA Kit

The PDCD4 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor PDCD4 protein expression profile in cells. The kit can be used for measuring the relative amounts of PDCD4 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on PDCD4.

Product Specifications

Synonyms

Programmed cell death protein 4; Neoplastic transformation inhibitor protein; Nuclear antigen H731-like; Protein 197/15a; PDCD4; H731

Gene Name

PDCD4

UniProt

Q53EL6

Reactivity

Human, Mouse, Rat

Tissue Specificity

Up-regulated in proliferative cells. Highly expressed in epithelial cells of the mammary gland. Reduced expression in lung cancer and colon carcinoma.

Applications

ELISA

Detection Range

> 5000 cells/well

Function

Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription. May play a role in apoptosis. Tumor suppressor. Inhibits tumor promoter-induced neoplastic transformation. Binds RNA (By similarity) .

Molecular Weight

51735 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Other Gene Names

Programmed cell death protein 4

Subcellular Location

Nucleus. Cytoplasm. Shuttles between the nucleus and cytoplasm (By similarity) . Predominantly nuclear under normal growth conditions, and when phosphorylated at Ser-457 (PubMed:16357133) .

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Sub Antibody
orb807807 2 mg

Sub Antibody

Sign In for Pricing
View Details
SNS-032
289085-01 5 mg

SNS-032

Sign In for Pricing
View Details
SNS-032
289085-02 10 mg

SNS-032

Sign In for Pricing
View Details
SNS-032
289085-03 25 mg

SNS-032

Sign In for Pricing
View Details
SNS-032
289085-04 50 mg

SNS-032

Sign In for Pricing
View Details
SNS-032
289085-05 100 mg

SNS-032

Sign In for Pricing
View Details