P56 Dok-2 Colorimetric Cell-Based ELISA Kit
The p56 Dok-2 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor p56 Dok-2 protein expression profile in cells. The kit can be used for measuring the relative amounts of p56 Dok-2 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on p56 Dok-2.
Product Specifications
Synonyms
Docking protein 2; Downstream of tyrosine kinase 2; p56 (dok-2) ; DOK2
Gene Name
DOK2
UniProt
O60496
Reactivity
Human, Mouse
Tissue Specificity
Highly expressed in peripheral blood leukocytes, lymph nodes and spleen. Lower expression in thymus, bone marrow and fetal liver.
Applications
ELISA
Detection Range
> 5000 cells/well
Function
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK2 may modulate the cellular proliferation induced by IL-4, as well as IL-2 and IL-3. May be involved in modulating Bcr-Abl signaling. Attenuates EGF-stimulated MAP kinase activation (By similarity) .
Molecular Weight
45379 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Docking protein 2
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