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P47 phox Colorimetric Cell-Based ELISA Kit

The p47 phox Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor p47 phox protein expression profile in cells. The kit can be used for measuring the relative amounts of p47 phox in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on p47 phox.

Product Specifications

Synonyms

Neutrophil cytosol factor 1; NCF-1;47 kDa autosomal chronic granulomatous disease protein;47 kDa neutrophil oxidase factor; NCF-47K; Neutrophil NADPH oxidase factor 1; Nox organizer 2; Nox-organizing protein 2; SH3 and PX domain-containing protein 1A; p47-phox; NCF1; NOXO2, SH3PXD1A

Gene Name

NCF1

UniProt

P14598

Reactivity

Human

Tissue Specificity

Detected in peripheral blood monocytes and neutrophils (at protein level) .

Applications

ELISA

Detection Range

> 5000 cells/well

Function

NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production) .

Molecular Weight

44652 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Other Gene Names

Neutrophil cytosol factor 1

Subcellular Location

Cytoplasm, cytosol. Membrane; Peripheral membrane protein; Cytoplasmic side.

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