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NYREN18 Colorimetric Cell-Based ELISA Kit

The NYREN18 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor NYREN18 protein expression profile in cells. The kit can be used for measuring the relative amounts of NYREN18 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on NYREN18.

Product Specifications

Synonyms

NEDD8 ultimate buster 1; Negative regulator of ubiquitin-like proteins 1; Renal carcinoma antigen NY-REN-18; NUB1; NYREN18

Gene Name

NUB1

UniProt

Q9Y5A7

Reactivity

Human, Mouse

Tissue Specificity

Widely expressed with lowest expression in the pancreas for isoform 1 and in leukocytes, liver, prostate and skeletal muscle for isoform 2.

Applications

ELISA

Detection Range

> 5000 cells/well

Function

Specific down-regulator of the NEDD8 conjugation system. Recruits NEDD8, UBD, and their conjugates to the proteasome for degradation. Isoform 1 promotes the degradation of NEDD8 more efficiently than isoform 2.

Molecular Weight

70538 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Other Gene Names

NEDD8 ultimate buster 1

Subcellular Location

Nucleus. Predominantly nuclear.

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