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Nuclear Receptor NR4A1 Colorimetric Cell-Based ELISA Kit

The Nuclear Receptor NR4A1 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor Nuclear Receptor NR4A1 protein expression profile in cells. The kit can be used for measuring the relative amounts of Nuclear Receptor NR4A1 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on Nuclear Receptor NR4A1.

Product Specifications

Synonyms

Nuclear receptor subfamily 4 group A member 1; Early response protein NAK1; Nuclear hormone receptor NUR/77; Nur77; Orphan nuclear receptor HMR; Orphan nuclear receptor TR3; ST-59; Testicular receptor 3; NR4A1; GFRP1, HMR, NAK1

Gene Name

NR4A1

UniProt

P22736

Reactivity

Human, Mouse, Rat

Tissue Specificity

Fetal muscle and adult liver, brain and thyroid.

Applications

ELISA

Detection Range

> 5000 cells/well

Function

Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'- AAAAGGTCA-3' (By similarity) . May inhibit NF-kappa-B transactivation of IL2. Participates in energy homeostasis by sequestrating the kinase STK11 in the nucleus, thereby attenuating cytoplasmic AMPK activation. Plays a role in the vascular response to injury (By similarity) .

Molecular Weight

64463 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Other Gene Names

Nuclear receptor subfamily 4 group A member 1

Subcellular Location

Nucleus. Cytoplasm. Nuclear export to the cytoplasm is XPO1-mediated and positively regulated by IFI27.

Frequently Asked Questions

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