NEK9 Colorimetric Cell-Based ELISA Kit
The NEK9 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor NEK9 protein expression profile in cells. The kit can be used for measuring the relative amounts of NEK9 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on NEK9.
Product Specifications
Synonyms
Serine/threonine-protein kinase Nek9;2.7.11.1; Nercc1 kinase; Never in mitosis A-related kinase 9; NimA-related protein kinase 9; NimA-related kinase 8; Nek8; NEK9; KIAA1995, NEK8, NERCC
Gene Name
NEK9
UniProt
Q8TD19
Reactivity
Human, Mouse, Rat
Tissue Specificity
Most abundant in heart, liver, kidney and testis. Also expressed in smooth muscle cells and fibroblasts.
Applications
ELISA
Detection Range
> 5000 cells/well
Function
Pleiotropic regulator of mitotic progression, participating in the control of spindle dynamics and chromosome separation. Phosphorylates different histones, myelin basic protein, beta-casein, and BICD2. Phosphorylates histone H3 on serine and threonine residues and beta-casein on serine residues. Important for G1/S transition and S phase progression. Phosphorylates NEK6 and NEK7 and stimulates their activity by releasing the autoinhibitory functions of Tyr-108 and Tyr-97 respectively.
Molecular Weight
107168 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Serine/threonine-protein kinase Nek9
Subcellular Location
Cytoplasm. Nucleus.
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