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MYT1 Colorimetric Cell-Based ELISA Kit

The MYT1 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor MYT1 protein expression profile in cells. The kit can be used for measuring the relative amounts of MYT1 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on MYT1.

Product Specifications

Synonyms

Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase;2.7.11.1; Myt1 kinase; PKMYT1; MYT1

Gene Name

PKMYT1

UniProt

Q99640

Reactivity

Human

Applications

ELISA

Detection Range

> 5000 cells/well

Function

Acts as a negative regulator of entry into mitosis (G2 to M transition) by phosphorylation of the CDK1 kinase specifically when CDK1 is complexed to cyclins. Mediates phosphorylation of CDK1 predominantly on 'Thr-14'. Also involved in Golgi fragmentation. May be involved in phosphorylation of CDK1 on 'Tyr-15' to a lesser degree, however tyrosine kinase activity is unclear and may be indirect. May be a downstream target of Notch signaling pathway during eye development.

Molecular Weight

54521 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=EKC1394

Product MSDS

https://www.bosterbio.com/msds?sku=EKC1394

Other Gene Names

Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase

Subcellular Location

Endoplasmic reticulum membrane; Peripheral membrane protein. Golgi apparatus membrane; Peripheral membrane protein.

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