MYPT1 Colorimetric Cell-Based ELISA Kit

The MYPT1 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor MYPT1 protein expression profile in cells. The kit can be used for measuring the relative amounts of MYPT1 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on MYPT1.

Product Specifications

Synonyms

Protein phosphatase 1 regulatory subunit 12A; Myosin phosphatase-targeting subunit 1; Myosin phosphatase target subunit 1; Protein phosphatase myosin-binding subunit; PPP1R12A ; MBS, MYPT1

Gene Name

PPP1R12A MBS, MYPT1

UniProt

O14974

Reactivity

Human, Mouse, Rat

Tissue Specificity

Expressed in striated muscles, specifically in type 2a fibers (at protein level) .

Applications

ELISA

Detection Range

> 5000 cells/well

Function

Key regulator of protein phosphatase 1C (PPP1C) . Mediates binding to myosin. As part of the PPP1C complex, involved in dephosphorylation of PLK1. Capable of inhibiting HIF1AN- dependent suppression of HIF1A activity.