MYPT1 Colorimetric Cell-Based ELISA Kit
The MYPT1 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor MYPT1 protein expression profile in cells. The kit can be used for measuring the relative amounts of MYPT1 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on MYPT1.
Product Specifications
Synonyms
Protein phosphatase 1 regulatory subunit 12A; Myosin phosphatase-targeting subunit 1; Myosin phosphatase target subunit 1; Protein phosphatase myosin-binding subunit; PPP1R12A ; MBS, MYPT1
Gene Name
PPP1R12A MBS, MYPT1
UniProt
O14974
Reactivity
Human, Mouse, Rat
Tissue Specificity
Expressed in striated muscles, specifically in type 2a fibers (at protein level) .
Applications
ELISA
Detection Range
> 5000 cells/well
Function
Key regulator of protein phosphatase 1C (PPP1C) . Mediates binding to myosin. As part of the PPP1C complex, involved in dephosphorylation of PLK1. Capable of inhibiting HIF1AN- dependent suppression of HIF1A activity.
Molecular Weight
115281 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Protein phosphatase 1 regulatory subunit 12A
Subcellular Location
Cytoplasm. Along actomyosin filaments and stress fibers.
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