MKP-1/2 Colorimetric Cell-Based ELISA Kit

The MKP-1/2 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor MKP-1/2 protein expression profile in cells. The kit can be used for measuring the relative amounts of MKP-1/2 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on MKP-1/2.

Product Specifications

Synonyms

3CH134; CL100; Dual specificity protein phosphatase 1; Dual specificity protein phosphatase hVH1; DUS1; DUSP1; MAP kinase phosphatase-1; MKP1; Protein-tyrosine phosphatase 3CH134; Protein-tyrosine phosphatase CL100; Protein-tyrosine phosphatase ERP; PTPN10; PTPN16; VH1

Gene Name

DUSP1 CL100 , MKP1, PTPN10 , VH1

UniProt

P28562

Reactivity

Human, Mouse, Rat

Tissue Specificity

Expressed at high levels in the lung, liver placenta and pancreas. Moderate levels seen in the heart and skeletal muscle. Lower levels found in the brain and kidney.

Applications

ELISA

Sample Type

Cell lines

Detection Range

> 5000 cells/well

Function

Dual specificity phosphatase that dephosphorylates MAP kinase MAPK1/ERK2 on both 'Thr-183' and 'Tyr-185', regulating its activity during the meiotic cell cycle.