MGluR6 Colorimetric Cell-Based ELISA Kit
The mGluR6 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor mGluR6 protein expression profile in cells. The kit can be used for measuring the relative amounts of mGluR6 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on mGluR6.
Product Specifications
Synonyms
CSNB1B; Glu6; GPRC1F; metabotropic glutamate receptor 6
Gene Name
GRM6
UniProt
O15303
Reactivity
Human
Tissue Specificity
Detected in melanocytes.
Applications
ELISA
Sample Type
Cell lines
Detection Range
> 5000 cells/well
Function
G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity (By similarity) . Signaling stimulates TRPM1 channel activity and Ca (2+) uptake. Required for normal vision.
Molecular Weight
95468 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Metabotropic glutamate receptor 6
Subcellular Location
Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cell projection, dendrite. Subject to trafficking from the endoplasmic reticulum to the Golgi apparatus and then to the cell membrane.
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