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MGluR4 Colorimetric Cell-Based ELISA Kit

The mGluR4 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor mGluR4 protein expression profile in cells. The kit can be used for measuring the relative amounts of mGluR4 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on mGluR4.

Product Specifications

Synonyms

Metabotropic glutamate receptor 4; mGluR4; GPRC1D; MGLUR4; GRM4

Gene Name

GRM4

UniProt

Q14833

Reactivity

Human, Mouse, Rat

Tissue Specificity

Strongly expressed in the cerebellum. Expressed at low levels in hippocampus, hypothalamus and thalamus. No expression detected in liver.

Applications

ELISA

Sample Type

Cell lines

Detection Range

> 5000 cells/well

Function

G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.

Molecular Weight

101868 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Other Gene Names

Metabotropic glutamate receptor 4

Subcellular Location

Cell membrane; Multi-pass membrane protein.

Frequently Asked Questions

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