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MGluR2/3 Colorimetric Cell-Based ELISA Kit

The mGluR2/3 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor mGluR2/3 protein expression profile in cells. The kit can be used for measuring the relative amounts of mGluR2/3 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on mGluR2/3.

Product Specifications

Synonyms

GPRC1C; GRM3; MGR3; Metabotropic glutamate receptor 3 precursor; glutamate receptor metabotropic type 3

Gene Name

GRM2

UniProt

Q14416

Reactivity

Human, Mouse, Rat

Tissue Specificity

Detected in brain cortex (at protein level) . Widely expressed in different regions of the adult brain as well as in fetal brain.

Applications

ELISA

Sample Type

Cell lines

Detection Range

> 5000 cells/well

Function

G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization.

Molecular Weight

95568 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Other Gene Names

Metabotropic glutamate receptor 2

Subcellular Location

Cell membrane; Multi-pass membrane protein. Cell junction, synapse. Cell projection, dendrite.

Frequently Asked Questions

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