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Keratin 19 Colorimetric Cell-Based ELISA Kit

The Keratin 19 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor Keratin 19 protein expression profile in cells. The kit can be used for measuring the relative amounts of Keratin 19 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on Keratin 19.

Product Specifications

Synonyms

Keratin type I cytoskeletal 19; Cytokeratin-19; CK-19; K19; KRT19

Gene Name

KRT19

UniProt

P08727

Reactivity

Human, Mouse, Rat

Tissue Specificity

Expressed in a defined zone of basal keratinocytes in the deep outer root sheath of hair follicles. Also observed in sweat gland and mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, ectocervical epithelium (at protein level) . Expressed in epidermal basal cells, in nipple epidermis and a defined region of the hair follicle. Also seen in a subset of vascular wall cells in both the veins and artery of human umbilical cord, and in umbilical cord vascular smooth muscle. Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma in structures that contain dystrophin and spectrin.

Applications

ELISA

Sample Type

Cell lines

Detection Range

> 5000 cells/well

Function

Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.

Molecular Weight

44106 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Other Gene Names

Keratin, type I cytoskeletal 19

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