IkappaB-beta Colorimetric Cell-Based ELISA Kit
The IkappaB-beta Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor IkappaB-beta protein expression profile in cells. The kit can be used for measuring the relative amounts of IkappaB-beta in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on IkappaB-beta.
Product Specifications
Synonyms
I-kappa-B-beta; IKB-B; IKBB; IkappaBbeta; NF-kappa-BIB; NF-kappaB inhibitor beta; NFKBIB; TR- interacting protein 9; TRIP9; Thyroid receptor interacting protein 9
Gene Name
NFKBIB
UniProt
Q15653
Reactivity
Human, Mouse
Tissue Specificity
Expressed in all tissues examined.
Applications
ELISA
Sample Type
Cell lines
Detection Range
> 5000 cells/well
Function
Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA- dependent inactivation. Association with inhibitor kappa B- interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.
Molecular Weight
37771 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
NF-kappa-B inhibitor beta
Subcellular Location
Cytoplasm. Nucleus.
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