IRS-1 Colorimetric Cell-Based ELISA Kit
The IRS-1 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor IRS-1 protein expression profile in cells. The kit can be used for measuring the relative amounts of IRS-1 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on IRS-1.
Product Specifications
Synonyms
Insulin receptor substrate-1; IRS-1; IRS1
Gene Name
IRS1
UniProt
P35568
Reactivity
Human, Mouse, Rat
Applications
ELISA
Sample Type
Cell lines
Detection Range
> 5000 cells/well
Function
May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit (By similarity) .
Molecular Weight
131591 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Insulin receptor substrate 1
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