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Interferon-gamma Receptor alpha Colorimetric Cell-Based ELISA Kit

The Interferon-gamma Receptor alpha Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor Interferon-gamma Receptor alpha protein expression profile in cells. The kit can be used for measuring the relative amounts of Interferon-gamma Receptor alpha in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on Interferon-gamma Receptor alpha.

Product Specifications

Synonyms

CD119 antigen; CDw119; IFN-gamma-R1; INGR; INGR1; Interferon-gamma receptor alpha chain precursor

Gene Name

IFNGR1

UniProt

P15260

Reactivity

Human, Mouse, Rat

Applications

ELISA

Sample Type

Cell lines

Detection Range

> 5000 cells/well

Function

Associates with IFNGR2 to form a receptor for the cytokine interferon gamma (IFNG) (PubMed:7615558, PubMed:2971451, PubMed:7617032, PubMed:10986460) . Ligand binding stimulates activation of the JAK/STAT signaling pathway (PubMed:7673114) . Plays an essential role in the IFN-gamma pathway that is required for the cellular response to infectious agents (PubMed:20015550) .

Molecular Weight

54405 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Other Gene Names

Interferon gamma receptor 1

Subcellular Location

Cell membrane; Single-pass type I membrane protein.

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