Histone H2B Colorimetric Cell-Based ELISA Kit
The Histone H2B Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor Histone H2B protein expression profile in cells. The kit can be used for measuring the relative amounts of Histone H2B in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on Histone H2B.
Product Specifications
Synonyms
Histone H2B type F-S; Histone H2B.s; H2B/s; H2BFS
Gene Name
HIST1H2BB
UniProt
P33778
Reactivity
Human, Mouse
Applications
ELISA
Sample Type
Cell lines
Detection Range
> 5000 cells/well
Function
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Molecular Weight
13950 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Histone H2B type 1-B
Subcellular Location
Nucleus. Chromosome.
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