HAT Colorimetric Cell-Based ELISA Kit
The HAT Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor HAT protein expression profile in cells. The kit can be used for measuring the relative amounts of HAT in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on HAT.
Product Specifications
Synonyms
Histone acetyltransferase 1; histone acetyltransferase type B catalytic; KAT1
Gene Name
HAT1
UniProt
O14929
Reactivity
Human, Mouse, Rat
Applications
ELISA
Sample Type
Cell lines
Detection Range
> 5000 cells/well
Function
Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac) . Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. May be involved in nucleosome assembly during DNA replication and repair as part of the histone H3.1 and H3.3 complexes. May play a role in DNA repair in response to free radical damage.
Molecular Weight
49513 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Histone acetyltransferase type B catalytic subunit
Subcellular Location
Isoform A: Nucleus matrix.
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