Glucagon Colorimetric Cell-Based ELISA Kit

The Glucagon Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor Glucagon protein expression profile in cells. The kit can be used for measuring the relative amounts of Glucagon in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on Glucagon.

Product Specifications

Synonyms

Glucagon; GCG

Gene Name

GCG

UniProt

P01275

Reactivity

Human, Mouse, Rat

Tissue Specificity

Glucagon is secreted in the A cells of the islets of Langerhans. GLP-1, GLP-2, oxyntomodulin and glicentin are secreted from enteroendocrine cells throughout the gastrointestinal tract. GLP-1 and GLP-2 are also secreted in selected neurons in the brain.

Applications

ELISA

Sample Type

Cell lines

Detection Range

> 5000 cells/well

Function

Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia. Plays an important role in initiating and maintaining hyperglycemic conditions in diabetes.