GIRK1/KIR3.1/KCNJ3 Colorimetric Cell-Based ELISA Kit
The GIRK1/KIR3.1/KCNJ3 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor GIRK1/KIR3.1/KCNJ3 protein expression profile in cells. The kit can be used for measuring the relative amounts of GIRK1/KIR3.1/KCNJ3 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on GIRK1/KIR3.1/KCNJ3.
Product Specifications
Synonyms
G protein-activated inward rectifier potassium channel 1; IRK3; Inward rectifier K channel Kir3.1; KCNJ3; Kir3.1; Potassium channel; inwardly rectifying, subfamily J, member 3
Gene Name
KCNJ3
UniProt
P48549
Reactivity
Human, Mouse, Rat
Applications
ELISA
Sample Type
Cell lines
Detection Range
> 5000 cells/well
Function
This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.
Molecular Weight
56603 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
G protein-activated inward rectifier potassium channel 1
Subcellular Location
Membrane; Multi-pass membrane protein.
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