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GIRK1/KIR3.1/KCNJ3 Colorimetric Cell-Based ELISA Kit

The GIRK1/KIR3.1/KCNJ3 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor GIRK1/KIR3.1/KCNJ3 protein expression profile in cells. The kit can be used for measuring the relative amounts of GIRK1/KIR3.1/KCNJ3 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on GIRK1/KIR3.1/KCNJ3.

Product Specifications

Synonyms

G protein-activated inward rectifier potassium channel 1; IRK3; Inward rectifier K channel Kir3.1; KCNJ3; Kir3.1; Potassium channel; inwardly rectifying, subfamily J, member 3

Gene Name

KCNJ3

UniProt

P48549

Reactivity

Human, Mouse, Rat

Applications

ELISA

Sample Type

Cell lines

Detection Range

> 5000 cells/well

Function

This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.

Molecular Weight

56603 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=EKC1239

Product MSDS

https://www.bosterbio.com/msds?sku=EKC1239

Other Gene Names

G protein-activated inward rectifier potassium channel 1

Subcellular Location

Membrane; Multi-pass membrane protein.

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