GATA1 Colorimetric Cell-Based ELISA Kit

The GATA1 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor GATA1 protein expression profile in cells. The kit can be used for measuring the relative amounts of GATA1 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on GATA1.

Product Specifications

Synonyms

Erythroid transcription factor; Eryf1; GATA-binding factor 1; GATA-1; GF-1; NF-E1 DNA-binding protein; GATA1; ERYF1; GF1

Gene Name

GATA1

UniProt

P15976

Reactivity

Human, Mouse, Rat

Tissue Specificity

Erythrocytes.

Applications

ELISA

Sample Type

Cell lines

Detection Range

> 5000 cells/well

Function

Transcriptional activator or repressor which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of globin genes and of other genes expressed in erythroid cells. Activates the transcription of genes involved in erythroid differentiation of K562 erythroleukemia cells, including HBB, HBG1/2, ALAS2 and HMBS (PubMed:24245781) .