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Galectin 3 Colorimetric Cell-Based ELISA Kit

The Galectin 3 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor Galectin 3 protein expression profile in cells. The kit can be used for measuring the relative amounts of Galectin 3 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on Galectin 3.

Product Specifications

Synonyms

35 kDa lectin; CBP 35; Carbohydrate binding protein 35; GALBP; Galactose-specific lectin 3; Galactoside-binding protein; IgE-binding protein; L-31; L-34 galactoside-binding lectin; LEG3; LGALS3; Laminin-binding protein; Lectin L-29; MAC-2 antigen; MAC2

Gene Name

LGALS3

UniProt

P17931

Reactivity

Human, Mouse, Rat

Tissue Specificity

A major expression is found in the colonic epithelium. It is also abundant in the activated macrophages. Expressed in fetal membranes.

Applications

ELISA

Sample Type

Cell lines

Detection Range

> 5000 cells/well

Function

Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity) . In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.

Molecular Weight

26152 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Other Gene Names

Galectin-3

Subcellular Location

Cytoplasm. Nucleus. Secreted. Secreted by a non-classical secretory pathway and associates with the cell surface.

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