FRS2 Colorimetric Cell-Based ELISA Kit
The FRS2 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor FRS2 protein expression profile in cells. The kit can be used for measuring the relative amounts of FRS2 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on FRS2.
Product Specifications
Synonyms
FGFR signalling adaptor; FGFR signalling adaptor SNT-1; SNT-1; SNT2; SUC1-associated neurotrophic factor target; Suc1-associated neurotrophic factor target
Gene Name
FRS2
UniProt
Q8WU20
Reactivity
Human, Mouse
Tissue Specificity
Highly expressed in heart, brain, spleen, lung, liver, skeletal muscle, kidney and testis.
Applications
ELISA
Sample Type
Cell lines
Detection Range
> 5000 cells/well
Function
Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3- kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.
Molecular Weight
57029 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Fibroblast growth factor receptor substrate 2
Subcellular Location
Endomembrane system. Cytoplasmic, membrane-bound.
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