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ERK3 Colorimetric Cell-Based ELISA Kit

The ERK3 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor ERK3 protein expression profile in cells. The kit can be used for measuring the relative amounts of ERK3 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on ERK3.

Product Specifications

Synonyms

ERK-3; ERK3; Extracellular signal- regulated kinase 3; MAP kinase isoform p97; MAPK6; MK06; Mitogen-activated protein kinase 6; PRKM4; PRKM6; kinase ERK3; p55-MAPK; p97-MAPK

Gene Name

MAPK6

UniProt

Q16659

Reactivity

Human, Mouse, Rat

Tissue Specificity

Highest expression in the skeletal muscle, followed by the brain. Also found in heart, placenta, lung, liver, pancreas, kidney and skin fibroblasts.

Applications

ELISA

Sample Type

Cell lines

Detection Range

> 5000 cells/well

Function

Atypical MAPK protein. Phosphorylates microtubule- associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK3/MAPK6 is phosphorylated at Ser-189 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK3/MAPK6. May promote entry in the cell cycle (By similarity) .

Molecular Weight

82681 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=EKC1200

Product MSDS

https://www.bosterbio.com/msds?sku=EKC1200

Other Gene Names

Mitogen-activated protein kinase 6

Subcellular Location

Cytoplasm. Nucleus. Translocates to the cytoplasm following interaction with MAPKAPK5.

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