ERCC1 Colorimetric Cell-Based ELISA Kit

Cofs4; ercc1; excision repair cross-complementing 1; excision repair cross-complementing 1 isoform 1; excision repair cross-complementing 1 isofrom 2; excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence) excision repair protein; uv20

Isoform 1: Non-catalytic component of a structure- specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. Responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links (ICL) . Participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. Also required for homology-directed repair (HDR) of DNA double-strand breaks, in conjunction with SLX4.