ERAB Colorimetric Cell-Based ELISA Kit

3-hydroxyacyl-CoA dehydrogenase type-2;3-hydroxyacyl-CoA dehydrogenase type II; Type II HADH;3-hydroxy-2-methylbutyryl-CoA dehydrogenase;17-beta-hydroxysteroid dehydrogenase 10; Mitochondrial ribonuclease P protein 2; Endoplasmic reticulum-associated amyloid beta-peptide-binding protein; Short-chain type dehydrogenase/reductase XH98G2; HSD17B10ERAB; HADH2; MRPP2; SCHAD; XH98G2

Mitochondrial dehydrogenase that catalyzes the beta- oxidation at position 17 of androgens and estrogens and has 3- alpha-hydroxysteroid dehydrogenase activity with androsterone (PubMed:9553139, PubMed:23042678, PubMed:12917011, PubMed:18996107, PubMed:25925575, PubMed:28888424) . Catalyzes the third step in the beta-oxidation of fatty acids (PubMed:9553139, PubMed:12917011, PubMed:18996107, PubMed:25925575, PubMed:28888424) . Carries out oxidative conversions of 7-alpha-OH and 7-beta-OH bile acids (PubMed:12917011) . Also exhibits 20-beta- OH and 21-OH dehydrogenase activities with C21 steroids (PubMed:12917011) . By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease (AD) (PubMed:9338779) . Essential for structural and functional integrity of mitochondria (PubMed:20077426) .