What is the catalog number for ERAB Colorimetric Cell-Based ELISA Kit?

The catalog number for ERAB Colorimetric Cell-Based ELISA Kit is EKC1198.

What sizes are available for ERAB Colorimetric Cell-Based ELISA Kit?

ERAB Colorimetric Cell-Based ELISA Kit is available in the following size(s): 1 Kit, containing one 96 Well Plate and all necessary reagents.

Is ERAB Colorimetric Cell-Based ELISA Kit in stock?

ERAB Colorimetric Cell-Based ELISA Kit is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for ERAB Colorimetric Cell-Based ELISA Kit?

The safety data sheet for ERAB Colorimetric Cell-Based ELISA Kit is available here: https://www.bosterbio.com/msds?sku=EKC1198.

ERAB Colorimetric Cell-Based ELISA Kit

The ERAB Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor ERAB protein expression profile in cells. The kit can be used for measuring the relative amounts of ERAB in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on ERAB.

Product Specifications

Synonyms

3-hydroxyacyl-CoA dehydrogenase type-2;3-hydroxyacyl-CoA dehydrogenase type II; Type II HADH;3-hydroxy-2-methylbutyryl-CoA dehydrogenase;17-beta-hydroxysteroid dehydrogenase 10; Mitochondrial ribonuclease P protein 2; Endoplasmic reticulum-associated amyloid beta-peptide-binding protein; Short-chain type dehydrogenase/reductase XH98G2; HSD17B10ERAB; HADH2; MRPP2; SCHAD; XH98G2

Gene Name

HSD17B10

UniProt

Q99714

Reactivity

Human, Mouse, Rat

Tissue Specificity

Ubiquitously expressed in normal tissues but is overexpressed in neurons affected in AD.

Applications

ELISA

Sample Type

Cell lines

Detection Range

> 5000 cells/well

Function

Mitochondrial dehydrogenase that catalyzes the beta- oxidation at position 17 of androgens and estrogens and has 3- alpha-hydroxysteroid dehydrogenase activity with androsterone (PubMed:9553139, PubMed:23042678, PubMed:12917011, PubMed:18996107, PubMed:25925575, PubMed:28888424) . Catalyzes the third step in the beta-oxidation of fatty acids (PubMed:9553139, PubMed:12917011, PubMed:18996107, PubMed:25925575, PubMed:28888424) . Carries out oxidative conversions of 7-alpha-OH and 7-beta-OH bile acids (PubMed:12917011) . Also exhibits 20-beta- OH and 21-OH dehydrogenase activities with C21 steroids (PubMed:12917011) . By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease (AD) (PubMed:9338779) . Essential for structural and functional integrity of mitochondria (PubMed:20077426) .