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EPHB6 Colorimetric Cell-Based ELISA Kit

The EPHB6 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor EPHB6 protein expression profile in cells. The kit can be used for measuring the relative amounts of EPHB6 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on EPHB6.

Product Specifications

Synonyms

EPB6; Ephrin type-B receptor 6 precursor; HEP; Tyrosine-protein kinase-defective receptor EPH-6

Gene Name

EPHB6

UniProt

O15197

Reactivity

Human, Mouse, Rat

Tissue Specificity

Expressed in brain. Expressed in non invasive breast carcinoma cell lines (at protein level) . Strong expression in brain and pancreas, and weak expression in other tissues, such as heart, placenta, lung, liver, skeletal muscle and kidney. Expressed in breast non invasive tumors but not in metastatic lesions. Isoform 3 is expressed in cell lines of glioblastomas, anaplastic astrocytomas, gliosarcomas and astrocytomas. Isoform 3 is not detected in normal tissues.

Applications

ELISA

Sample Type

Cell lines

Detection Range

> 5000 cells/well

Function

Kinase-defective receptor for members of the ephrin-B family. Binds to ephrin-B1 and ephrin-B2. Modulates cell adhesion and migration by exerting both positive and negative effects upon stimulation with ephrin-B2. Inhibits JNK activation, T-cell receptor-induced IL-2 secretion and CD25 expression upon stimulation with ephrin-B2.

Molecular Weight

110700 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=EKC1196

Product MSDS

https://www.bosterbio.com/msds?sku=EKC1196

Other Gene Names

Ephrin type-B receptor 6

Subcellular Location

Membrane; Single-pass type I membrane protein.

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