EPB41 Colorimetric Cell-Based ELISA Kit
The EPB41 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor EPB41 protein expression profile in cells. The kit can be used for measuring the relative amounts of EPB41 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on EPB41.
Product Specifications
Synonyms
4.1R;41; band 4.1; E41P; EPB4.1; erythrocyte membrane protein band 4.1; P4.1; protein 4.1
Gene Name
EPB41
UniProt
P11171
Reactivity
Human, Mouse
Applications
ELISA
Sample Type
Cell lines
Detection Range
> 5000 cells/well
Function
Protein 4.1 is a major structural element of the erythrocyte membrane skeleton. It plays a key role in regulating membrane physical properties of mechanical stability and deformability by stabilizing spectrin-actin interaction. Recruits DLG1 to membranes. Required for dynein-dynactin complex and NUMA1 recruitment at the mitotic cell cortex during anaphase (PubMed:23870127) .
Molecular Weight
97017 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Protein 4.1
Subcellular Location
Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Nucleus.
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