EFNA4 Colorimetric Cell-Based ELISA Kit

The EFNA4 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor EFNA4 protein expression profile in cells. The kit can be used for measuring the relative amounts of EFNA4 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on EFNA4.

Product Specifications

Synonyms

EFL4; EPLG4; LERK4; ephrin-A4; eph-related receptor tyrosine kinase ligand 4; ephrin A4 isoform a; ephrin A4 isoform b; ephrin A4 isoform c; ligand of eph-related kinase 4

Gene Name

EFNA4

UniProt

P52798

Reactivity

Human, Mouse

Tissue Specificity

Expressed in the adult spleen, lymph node, prostate, ovary, small intestine, and colon, and in fetal heart, lung, liver and kidney. Also detected in hematopoietic cell lines.

Applications

ELISA

Sample Type

Cell lines

Detection Range

> 5000 cells/well

Function

Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. May play a role in the interaction between activated B-lymphocytes and dendritic cells in tonsils.