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DAPP1 Colorimetric Cell-Based ELISA Kit

The DAPP1 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor DAPP1 protein expression profile in cells. The kit can be used for measuring the relative amounts of DAPP1 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on DAPP1.

Product Specifications

Synonyms

3' phosphoinositide-interacting SH2 domain containing protein; B lymphocyte adapter protein BAM32; Bam32; Dual adaptor for phosphotyrosine and 3-phosphoinositides 1; PHISH; dual adapter for phosphotyrosine and 3-phosphoinositides

Gene Name

DAPP1

UniProt

Q9UN19

Reactivity

Human, Mouse

Tissue Specificity

Highly expressed in placenta and lung, followed by brain, heart, kidney, liver, pancreas and skeletal muscle. Expressed by B-lymphocytes, but not T-lymphocytes or nonhematopoietic cells.

Applications

ELISA

Sample Type

Cell lines

Detection Range

> 5000 cells/well

Function

May act as a B-cell-associated adapter that regulates B- cell antigen receptor (BCR) -signaling downstream of PI3K.

Molecular Weight

32194 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Other Gene Names

Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide

Subcellular Location

Cytoplasm. Membrane; Peripheral membrane protein. Membrane-associated after cell stimulation leading to its translocation.

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