CREB Colorimetric Cell-Based ELISA Kit
The CREB Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor CREB protein expression profile in cells. The kit can be used for measuring the relative amounts of CREB in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on CREB.
Product Specifications
Synonyms
CAMP responsive element binding protein 1; cAMP-response element binding protein; CREB-1; CREB1
Gene Name
CREB1
UniProt
P16220
Reactivity
Human, Mouse, Rat
Applications
ELISA
Sample Type
Cell lines
Detection Range
> 5000 cells/well
Function
Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.
Molecular Weight
36688 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Cyclic AMP-responsive element-binding protein 1
Subcellular Location
Nucleus.
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