Claudin 4 Colorimetric Cell-Based ELISA Kit
The Claudin 4 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor Claudin 4 protein expression profile in cells. The kit can be used for measuring the relative amounts of Claudin 4 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on Claudin 4.
Product Specifications
Synonyms
Claudin-4; CLD4; CLDN4; Clostridium perfringens enterotoxin receptor; CPE- receptor; CPE-R; CPER; CPETR1; WBSCR8; Williams-Beuren syndrome chromosome region 8 protein
Gene Name
CLDN4CPER , CPETR1 , WBSCR8
UniProt
O14493
Reactivity
Human, Mouse, Rat
Applications
ELISA
Sample Type
Cell lines
Detection Range
> 5000 cells/well
Function
Channel-forming tight junction protein that mediates paracellular chloride transport in the kidney. Plays a critical role in the paracellular reabsorption of filtered chloride in the kidney collecting ducts. Claudins play a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
Molecular Weight
22077 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Claudin-4
Subcellular Location
Cell junction, tight junction. Cell membrane; Multi-pass membrane protein. CLDN4 is required for tight junction localization in the kidney.
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